Tadalista 40 mg is a prescription medicine used to treat impotence, recognized medically as erectile dysfunction (ED), and indications of an enlarged prostate (benign prostatic hyperplasia, or BPH). It is also is used to change the strength to exercise in people with pulmonary arterial hypertension. Tadalafil 40 is in a combination of medications called phosphodiesterase 5 (PDE5) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. It may also decrease the prostate and bladder.